The Sustainable Synthesis of Organic Compounds: Iron-Catalyzed Enantioselective Carbon–Carbon Bond Formation
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The Sustainable Synthesis of Organic Compounds: Iron-Catalyzed Enantioselective Carbon–Carbon Bond Formation
PI: Gregory C. Fu
Division of Chemistry and Chemical Engineering
Sunlight to Everything Initiative
This project will investigate the development of a "green" method for the enantioselective formation of carbon–carbon bonds using a catalyst based on iron, the most earth-abundant transition metal, from readily available starting materials. Because carbon–carbon bonds form the primary backbone of most organic compounds, which play critical roles in fields such as pharmaceutical science, polymer chemistry, and biology, the discovery of versatile and efficient methods to generate carbon–carbon bonds under mild conditions (and control stereochemistry, when relevant) is a highly important objective for sustainable manufacturing.